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The Assembly and Maintenance of Heterochromatin Initiated by Transgene Repeats Are Independent of the RNA Interference Pathway in Mammalian Cells

A role for the RNA interference (RNAi) pathway in the establishment of heterochromatin is now well accepted for various organisms. Less is known about its relevance and precise role in mammalian cells. We previously showed that tandem insertion of a 1,000-copy inducible transgene into the genome of...

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書誌詳細
主要な著者: Wang, Fangwei, Koyama, Naoki, Nishida, Hiroko, Haraguchi, Tokuko, Reith, Walter, Tsukamoto, Toshiro
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489094/
https://ncbi.nlm.nih.gov/pubmed/16705157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02189-05
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