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HP1 cooperates with CAF-1 to compact heterochromatic transgene repeats in mammalian cells

The nuclear organization of tightly condensed heterochromatin plays important roles in regulating gene transcription and genome integrity. Heterochromatic domains are usually present at chromosomal regions containing a large array of repeated DNA sequences. We previously showed that integration of a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yan, Haiyan, Xiang, Xingfeng, Chen, Qinfu, Pan, Xuan, Cheng, Hankun, Wang, Fangwei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6147918/
https://ncbi.nlm.nih.gov/pubmed/30237539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32381-7
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