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Inhibition of synapse assembly in mammalian muscle in vivo by RNA interference
The formation of the vertebrate neuromuscular junction (NMJ) requires the receptor tyrosine kinase MuSK and the adaptor molecule rapsyn. Here, we report that the phenotypes of mice deficient in these two molecules can be reproduced by RNA interference (RNAi) in rat muscle in vivo. Specifically, doub...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1298976/ https://ncbi.nlm.nih.gov/pubmed/14749715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400065 |
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