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Characterization of the Multiple Conformational States of Free Monomeric and Trimeric Human Immunodeficiency Virus Envelope Glycoproteins after Fixation by Cross-Linker

The human immunodeficiency virus type 1 (HIV-1) gp120 exterior and gp41 transmembrane envelope glycoproteins assemble into trimers on the virus surface that represent potential targets for antibodies. Potent neutralizing antibodies bind the monomeric gp120 glycoprotein with small changes in entropy,...

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Détails bibliographiques
Auteurs principaux: Yuan, Wen, Bazick, Jessica, Sodroski, Joseph
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489074/
https://ncbi.nlm.nih.gov/pubmed/16809278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00118-06
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