Highly Stable Trimers Formed by Human Immunodeficiency Virus Type 1 Envelope Glycoproteins Fused with the Trimeric Motif of T4 Bacteriophage Fibritin

The envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) function as a trimer composed of three gp120 exterior glycoproteins and three gp41 transmembrane proteins. Soluble gp140 glycoproteins composed of the uncleaved ectodomains of gp120 and gp41 form unstable, heterogeneous oligom...

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Detalhes bibliográficos
Main Authors: Yang, Xinzhen, Lee, Juliette, Mahony, Erin M., Kwong, Peter D., Wyatt, Richard, Sodroski, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155086/
https://ncbi.nlm.nih.gov/pubmed/11932429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.9.4634-4642.2002
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