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Ral Is both Necessary and Sufficient for the Inhibition of Myeloid Differentiation Mediated by Ras
Hyperactivation of Ras is one of the most common abnormalities in acute myeloid leukemia. In experimental models, Ras inhibits myeloid differentiation, which is characteristic of leukemia; however, the mechanism through which it disrupts hematopoiesis is poorly understood. In multipotent FDCP-mix ce...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1489015/ https://ncbi.nlm.nih.gov/pubmed/16648489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.10.3966-3975.2006 |
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