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Nickel Ions Increase Histone H3 Lysine 9 Dimethylation and Induce Transgene Silencing

We have previously reported that carcinogenic nickel compounds decreased global histone H4 acetylation and silenced the gpt transgene in G12 Chinese hamster cells. However, the nature of this silencing is still not clear. Here, we report that nickel ion exposure increases global H3K9 mono- and dimet...

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Detalhes bibliográficos
Main Authors: Chen, Haobin, Ke, Qingdong, Kluz, Thomas, Yan, Yan, Costa, Max
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1488989/
https://ncbi.nlm.nih.gov/pubmed/16648469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.10.3728-3737.2006
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