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Down-Regulation of the Expression of the FIH-1 and ARD-1 Genes at the Transcriptional Level by Nickel and Cobalt in the Human Lung Adenocarcinoma A549 Cell Line

Although nickel and cobalt compounds have been known to cause induction of the transcription factor hypoxia-inducible factor 1 (HIF-1) and activation of a battery of hypoxia-inducible genes in the cell, the molecular mechanisms of this induction remain unclear. The post-translational modification of...

詳細記述

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書誌詳細
主要な著者: Ke, Qingdong, Kluz, Thomas, Costa, Max
フォーマット: Artigo
言語:Inglês
出版事項: Molecular Diversity Preservation International (MDPI) 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814691/
https://ncbi.nlm.nih.gov/pubmed/16705796
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