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Down-Regulation of the Expression of the FIH-1 and ARD-1 Genes at the Transcriptional Level by Nickel and Cobalt in the Human Lung Adenocarcinoma A549 Cell Line

Although nickel and cobalt compounds have been known to cause induction of the transcription factor hypoxia-inducible factor 1 (HIF-1) and activation of a battery of hypoxia-inducible genes in the cell, the molecular mechanisms of this induction remain unclear. The post-translational modification of...

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Detaylı Bibliyografya
Asıl Yazarlar: Ke, Qingdong, Kluz, Thomas, Costa, Max
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Molecular Diversity Preservation International (MDPI) 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814691/
https://ncbi.nlm.nih.gov/pubmed/16705796
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