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Interleukin-12 Regulates Chemokine Gene Expression during the Early Immune Response to Leishmania major

Following infection with Leishmania major, the chemokines XCL1, CXCL10, and CCL2 were preferentially expressed in draining lymph nodes of resistant mice. Neutralization of interleukin 12 (IL-12) or gamma interferon in resistant mice resulted in decreased chemokine expression, while administration of...

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Pubblicato in:Infect Immun
Autori principali: Zaph, Colby, Scott, Phillip
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148858/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12595483/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.3.1587-1589.2003
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