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Interleukin-12 Regulates Chemokine Gene Expression during the Early Immune Response to Leishmania major

Following infection with Leishmania major, the chemokines XCL1, CXCL10, and CCL2 were preferentially expressed in draining lymph nodes of resistant mice. Neutralization of interleukin 12 (IL-12) or gamma interferon in resistant mice resulted in decreased chemokine expression, while administration of...

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Detalhes bibliográficos
Main Authors: Zaph, Colby, Scott, Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC148858/
https://ncbi.nlm.nih.gov/pubmed/12595483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.3.1587-1589.2003
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