Lipophilic pro-oligonucleotides are rapidly and efficiently internalized in HeLa cells.
Model t-Bu-SATE pro-dodecathymidines labeled with fluorescein and exhibiting various lipophilicities were evaluated for their uptake by cells in culture. Pro-oligonucleotides with appropriate lipophilicity were found to permeate across the HeLa cell membrane much more extensively than the control ph...
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| Yayımlandı: | Nucleic Acids Res |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
1999
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148675/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10497272/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.20.4071 |
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