Confluence-induced alterations in CpG island methylation in cultured normal human fibroblasts.

Growth constraint of bacterial and human cells has been shown to trigger genetic mutation. We questioned whether growth constraint might also trigger epigenetic mutation in the form of CpG island methylation. Logarithmically growing normal human fibro-blasts (NHF) displayed little (0-15%) CpG methyl...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Pieper, R O, Lester, K A, Fanton, C P
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1999
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148552/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454622/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.15.3229
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