Confluence-induced alterations in CpG island methylation in cultured normal human fibroblasts.

Growth constraint of bacterial and human cells has been shown to trigger genetic mutation. We questioned whether growth constraint might also trigger epigenetic mutation in the form of CpG island methylation. Logarithmically growing normal human fibro-blasts (NHF) displayed little (0-15%) CpG methyl...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Pieper, R O, Lester, K A, Fanton, C P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1999
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148552/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454622/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.15.3229
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