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Confluence-induced alterations in CpG island methylation in cultured normal human fibroblasts.

Growth constraint of bacterial and human cells has been shown to trigger genetic mutation. We questioned whether growth constraint might also trigger epigenetic mutation in the form of CpG island methylation. Logarithmically growing normal human fibro-blasts (NHF) displayed little (0-15%) CpG methyl...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Nucleic Acids Res
Ngā kaituhi matua: Pieper, R O, Lester, K A, Fanton, C P
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Oxford University Press 1999
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148552/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454622/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.15.3229
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