Inhibition of luciferase expression by synthetic hammerhead ribozymes and their cellular uptake.
Two synthetic hammerhead ribozymes, one unmodified and the other with 2"-modifications and four phosphorothioate groups, targeting a single GUA site in the luciferase mRNA, were compared for their inhibition of gene expression in cell cultureand their cellular uptake was also analysed. A HeLa X1/5 c...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148543/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454613/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.15.3159 |
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