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A non-isotopic assay for histone deacetylase activity.

Inhibitors of histone deacetylase (HD) bear great potential as new drugs due to their ability to modulate transcription and to induce apoptosis or differentiation in cancer cells. To study the activity of HD and the effect of potential inhibitors in vitro so far only radio-active assays have existed...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Hoffmann, K, Brosch, G, Loidl, P, Jung, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148421/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10198441/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.9.2057
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