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A non-isotopic assay for histone deacetylase activity.

Inhibitors of histone deacetylase (HD) bear great potential as new drugs due to their ability to modulate transcription and to induce apoptosis or differentiation in cancer cells. To study the activity of HD and the effect of potential inhibitors in vitro so far only radio-active assays have existed...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Hoffmann, K, Brosch, G, Loidl, P, Jung, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148421/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10198441/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.9.2057
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