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A non-isotopic assay for histone deacetylase activity.

Inhibitors of histone deacetylase (HD) bear great potential as new drugs due to their ability to modulate transcription and to induce apoptosis or differentiation in cancer cells. To study the activity of HD and the effect of potential inhibitors in vitro so far only radio-active assays have existed...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Hoffmann, K, Brosch, G, Loidl, P, Jung, M
Format: Artigo
Language:Inglês
Published: Oxford University Press 1999
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148421/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10198441/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.9.2057
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