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A non-isotopic assay for histone deacetylase activity.

Inhibitors of histone deacetylase (HD) bear great potential as new drugs due to their ability to modulate transcription and to induce apoptosis or differentiation in cancer cells. To study the activity of HD and the effect of potential inhibitors in vitro so far only radio-active assays have existed...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Hoffmann, K, Brosch, G, Loidl, P, Jung, M
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148421/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10198441/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.9.2057
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