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G-protein-coupled Receptor Agonists Activate Endogenous Phospholipase Cε and Phospholipase Cβ3 in a Temporally Distinct Manner

Phospholipase Cε (PLCε) is one of the newest members of the phosphatidylinositol-specific phospholipase C (PLC) family. Previous studies have suggested that G-protein-coupled receptors (GPCRs) stimulate phosphoinositide (PI) hydrolysis by activating PLCβ isoforms through G(q) family G proteins and G...

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Detalhes bibliográficos
Main Authors: Kelley, Grant G., Kaproth-Joslin, Katherine A., Reks, Sarah E., Smrcka, Alan V., Wojcikiewicz, Richard J. H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483126/
https://ncbi.nlm.nih.gov/pubmed/16314422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M507681200
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