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Hormonal regulation of phospholipase Cepsilon through distinct and overlapping pathways involving G12 and Ras family G-proteins.

PLCepsilon (phospholipase Cepsilon) is a novel PLC that has a CDC25 guanine nucleotide exchange factor domain and two RA (Ras-association) domains of which the second (RA2) is critical for Ras activation of the enzyme. In the present studies, we examined hormonal stimulation to elucidate receptor-me...

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Autors principals: Kelley, Grant G, Reks, Sarah E, Smrcka, Alan V
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223921/
https://ncbi.nlm.nih.gov/pubmed/14567755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031370
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