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Flexibility in a Drug Transport Accessory Protein: Molecular Dynamics Simulations of MexA
Drug resistance in Gram-negative bacteria may be conferred via efflux through a tripartite complex of an inner membrane pump, an outer membrane pore, and a periplasmic adaptor protein. These are AcrB, TolC, and AcrA, respectively, in Escherichia coli. In Pseudomonas aerugonisa, their homologs are Me...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Biophysical Society
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1483075/ https://ncbi.nlm.nih.gov/pubmed/16648168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.080010 |
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