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Downregulation of uPA, uPAR and MMP-9 using small, interfering, hairpin RNA (siRNA) inhibits glioma cell invasion, angiogenesis and tumor growth

The diffuse, extensive infiltration of malignant gliomas into the surrounding normal brain is believed to rely on modification of the proteolysis of extracellular matrix components. Our previous results clearly demonstrate that uPA, uPAR and MMP-9 concentrations increase significantly during tumor p...

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Bibliografske podrobnosti
Main Authors: Gondi, Christopher S., Lakka, Sajani S., Dinh, Dzung H., Olivero, William C., Gujrati, Meena, Rao, Jasti S.
Format: Artigo
Jezik:Inglês
Izdano: 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483066/
https://ncbi.nlm.nih.gov/pubmed/16804563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/s1740925x04000237
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