Adjuvant-dependent modulation of Th(1) and Th(2) responses to immunization with β-amyloid

The role of adjuvant on the T(h)1 and T(h)2 immune responses to Aβ-immunotherapy (Aβ(42) peptide) was examined in wild-type mice. Fine epitope analysis with overlapping oligomers of the Aβ(42) sequence identified the 1–15 region as a dominant B cell epitope. The 6–20 peptide was recognized only weak...

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Main Authors: Cribbs, David H., Ghochikyan, Anahit, Vasilevko, Vitaly, Tran, Mike, Petrushina, Irina, Sadzikava, Nadya, Babikyan, Davit, Kesslak, Patrick, Kieber-Emmons, Thomas, Cotman, Carl W., Agadjanyan, Michael G.
Format: Artigo
Sprog:Inglês
Udgivet: 2003
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483061/
https://ncbi.nlm.nih.gov/pubmed/12663680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxg049
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