The H-phosphonate approach to the solution phase synthesis of linear and cyclic oligoribonucleotides.
The solution phase synthesis of the tetraribonucleoside triphosphate r(ApCpGpU) 18 and the corresponding cyclic tetraribonucleotide 19 is described. The synthetic methodology is based on 5'- O -(DMTr)-2'- O -(Fpmp)-ribonucleoside-3'- H -phosphonate building blocks 10. Coupling, which is rapid and qu...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148274/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927727/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.4.963 |
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