The H-phosphonate approach to the solution phase synthesis of linear and cyclic oligoribonucleotides.

The solution phase synthesis of the tetraribonucleoside triphosphate r(ApCpGpU) 18 and the corresponding cyclic tetraribonucleotide 19 is described. The synthetic methodology is based on 5'- O -(DMTr)-2'- O -(Fpmp)-ribonucleoside-3'- H -phosphonate building blocks 10. Coupling, which is rapid and qu...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Reese, C B, Song, Q
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 1999
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148274/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927727/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.4.963
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