The H-phosphonate approach to the solution phase synthesis of linear and cyclic oligoribonucleotides.
The solution phase synthesis of the tetraribonucleoside triphosphate r(ApCpGpU) 18 and the corresponding cyclic tetraribonucleotide 19 is described. The synthetic methodology is based on 5'- O -(DMTr)-2'- O -(Fpmp)-ribonucleoside-3'- H -phosphonate building blocks 10. Coupling, which is rapid and qu...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
1999
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148274/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927727/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.4.963 |
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