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tRNA(His) guanylyltransferase catalyzes a 3′-5′ polymerization reaction that is distinct from G(−1) addition
Yeast tRNA(His) guanylyltransferase, Thg1, is an essential protein that adds a single guanine to the 5′ end (G(−1)) of tRNA(His). This G(−1) residue is required for aminoacylation of tRNA(His) by histidyl-tRNA synthetase, both in vitro and in vivo. The guanine nucleotide addition reaction catalyzed...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482633/ https://ncbi.nlm.nih.gov/pubmed/16731615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603068103 |
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