Minimal requirements for reverse polymerization and tRNA repair by tRNA(His) guanylyltransferase

tRNA(His) guanylyltransferase (Thg1) has unique reverse (3’-5’) polymerase activity occurring in all three domains of life. Most eukaryotic Thg1 homologs are essential genes involved in tRNA(His) maturation. These enzymes normally catalyze a single 5’ guanylation of tRNA(His) lacking the essential G...

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Dettagli Bibliografici
Pubblicato in:RNA Biol
Autori principali: Desai, Riddhi, Kim, Kunmo, Büchsenschütz, Hanna C., Chen, Allan W., Bi, Yumin, Mann, Mitchell R., Turk, Matthew A., Chung, Christina Z., Heinemann, Ilka U.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Review - Solicited
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103667/
https://ncbi.nlm.nih.gov/pubmed/28901837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1372076
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