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The appearance of pyrrolysine in tRNA(His) guanylyltransferase by neutral evolution

tRNA(His) guanylyltransferase (Thg1) post-transcriptionally adds a G (position −1) to the 5′-terminus of tRNA(His). The Methanosarcina acetivorans Thg1 (MaThg1) gene contains an in-frame TAG (amber) codon. Although a UAG codon typically directs translation termination, its presence in Methanosarcina...

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Hlavní autoři: Heinemann, Ilka U., O'Donoghue, Patrick, Madinger, Catherine, Benner, Jack, Randau, Lennart, Noren, Christopher J., Söll, Dieter
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795538/
https://ncbi.nlm.nih.gov/pubmed/19965368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912072106
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