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Redox sensor CtBP mediates hypoxia-induced tumor cell migration
The rapid growth and poor vascularization of solid tumors expose cancer cells to hypoxia, which promotes the metastatic phenotype by reducing intercellular adhesion and increasing cell motility and invasiveness. In this study, we found that hypoxia increased free NADH levels in cancer cells, promoti...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482560/ https://ncbi.nlm.nih.gov/pubmed/16740659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603269103 |
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