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Redox-dependent Brca1 transcriptional regulation by an NADH-sensor CtBP1
Carboxyl-terminal binding protein 1 (CtBP1) is a transcriptional co-repressor and metabolic sensory protein, which often represses tumor suppressor genes. Hence, we sought to determine if CtBP1 affects expression of the tumor suppressor Brca1 in head and neck tissue, as down-regulation of Brca1 begi...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081720/ https://ncbi.nlm.nih.gov/pubmed/20818429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.406 |
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