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The critical mutagenic translesion DNA polymerase Rev1 is highly expressed during G(2)/M phase rather than S phase
The Rev1 protein lies at the root of mutagenesis in eukaryotes. Together with DNA polymerase ζ (Rev3/7), Rev1 function is required for the active introduction of the majority of mutations into the genomes of eukaryotes from yeast to humans. Rev1 and polymerase ζ are error-prone translesion DNA polym...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482550/ https://ncbi.nlm.nih.gov/pubmed/16751278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510167103 |
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