p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors

Homology between p63 and p53 has suggested that these proteins might function similarly. However, the majority of data from human tumors have not supported a similar role for p63 in tumor suppression. To investigate this issue, we studied spontaneous tumorigenesis in p63+/− mice in both WT and p53-c...

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Detaylı Bibliyografya
Asıl Yazarlar: Keyes, William M., Vogel, Hannes, Koster, Maranke I., Guo, Xuecui, Qi, Yi, Petherbridge, Kristin M., Roop, Dennis R., Bradley, Allan, Mills, Alea A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2006
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482510/
https://ncbi.nlm.nih.gov/pubmed/16714381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602477103
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