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p63 is the molecular switch for initiation of an epithelial stratification program

Development of stratified epithelia, such as the epidermis, requires p63 expression. The p63 gene encodes isoforms that contain (TA) or lack (ΔN) a transactivation domain. We demonstrate that TAp63 isoforms are the first to be expressed during embryogenesis and are required for initiation of epithel...

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Detalhes bibliográficos
Main Authors: Koster, Maranke I., Kim, Soeun, Mills, Alea A., DeMayo, Francesco J., Roop, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC324418/
https://ncbi.nlm.nih.gov/pubmed/14729569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1165104
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