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p63 is the molecular switch for initiation of an epithelial stratification program
Development of stratified epithelia, such as the epidermis, requires p63 expression. The p63 gene encodes isoforms that contain (TA) or lack (ΔN) a transactivation domain. We demonstrate that TAp63 isoforms are the first to be expressed during embryogenesis and are required for initiation of epithel...
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| Pubblicato in: | Genes Dev |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC324418/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14729569/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1165104 |
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