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Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks
Cellular responses to DNA damage involve the relocalization of checkpoint proteins to DNA double-strand breaks (DSBs). The fission yeast checkpoint mediator protein Crb2, a homolog of mammalian 53BP1, forms ionizing radiation-induced nuclear foci (IRIF). The IRIF formation by Crb2 requires histone H...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482479/ https://ncbi.nlm.nih.gov/pubmed/16778077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1422606 |
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