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Structural basis of catalysis by monometalated methionine aminopeptidase
Methionine aminopeptidase (MetAP) removes the amino-terminal methionine residue from newly synthesized proteins, and it is a target for the development of antibacterial and anticancer agents. Available x-ray structures of MetAP, as well as other metalloaminopeptidases, show an active site containing...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1480431/ https://ncbi.nlm.nih.gov/pubmed/16769889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602433103 |
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