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A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation
Some genes on the inactive X chromosome escape silencing. One possible escape mechanism is that heterochromatization during X inactivation can be blocked by boundary elements. DNA insulators are candidates for blocking because they shield genes from influences of their chromosomal environment. To te...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1479543/ https://ncbi.nlm.nih.gov/pubmed/16777957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603754103 |
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