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Growth-regulated antisense transcription of the mouse thymidine kinase gene.

The expression of the salvage pathway enzyme thymidine kinase (TK) is very low in resting mammalian cells, but increases dramatically when growth-stimulated cells enter S phase. The 30-fold rise in TK mRNA levels in response to growth factors is due to a well-characterized transcriptional activation...

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Detalhes bibliográficos
Main Authors: Sutterluety, H, Bartl, S, Doetzlhofer, A, Khier, H, Wintersberger, E, Seiser, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC147947/
https://ncbi.nlm.nih.gov/pubmed/9776764
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