Mutation detection using a novel plant endonuclease.

We have discovered a useful new reagent for mutation detection, a novel nuclease CEL I from celery. It is specific for DNA distortions and mismatches from pH 6 to 9. Incision is on the 3'-side of the mismatch site in one of the two DNA strands in a heteroduplex. CEL I-like nucleases are found in man...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Oleykowski, C A, Bronson Mullins, C R, Godwin, A K, Yeung, A T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1998
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147896/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9753726/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.20.4597
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