An apyrimidinic site kinks DNA and triggers incision by endonuclease VII of phage T4.
Apurinic/apyrimidinic lesions (AP-sites) occur frequently in DNA, generated by physically and chemically induced or spontaneous loss of bases. Repair mechanisms have evolved in organisms to deal efficiently with AP-sites by first incising the DNA at the lesion, followed by excision and resynthesis o...
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| Vydáno v: | Nucleic Acids Res |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
1998
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| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147852/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742246/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.19.4432 |
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