Sequence specificity of the hammerhead ribozyme revisited; the NHH rule.
The sequence specificity of hammerhead ribozyme cleavage has been re-evaluated with respect to the NUH rule. Contrary to previous reports it was found that substrates with GAC triplets were also cleaved. This was established in three different sequence contexts. The rate of cleavage under single tur...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
1998
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147825/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9722629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.18.4116 |
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