Sequence specificity of the hammerhead ribozyme revisited; the NHH rule.

The sequence specificity of hammerhead ribozyme cleavage has been re-evaluated with respect to the NUH rule. Contrary to previous reports it was found that substrates with GAC triplets were also cleaved. This was established in three different sequence contexts. The rate of cleavage under single tur...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Kore, A R, Vaish, N K, Kutzke, U, Eckstein, F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1998
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147825/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9722629/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.18.4116
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