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Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase η on ATR checkpoint signaling

An essential component of the ATR (ataxia telangiectasia-mutated and Rad3-related)-activating structure is single-stranded DNA. It has been suggested that nucleotide excision repair (NER) can lead to activation of ATR by generating such a signal, and in yeast, DNA damage processing through the NER p...

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Detalhes bibliográficos
Main Authors: Bomgarden, Ryan D, Lupardus, Patrick J, Soni, Deena V, Yee, Muh-Ching, Ford, James M, Cimprich, Karlene A
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1478198/
https://ncbi.nlm.nih.gov/pubmed/16675950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601123
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