4'-Acylated thymidine 5'-triphosphates: a tool to increase selectivity towards HIV-1 reverse transcriptase.

4'-Acylated thymidines represent a new class of DNA chain terminators, since they have been shown to act as post-incorporation chain-terminating nucleotides despite the presence of a free 3'-hydroxyl group. Here, we describe the action of the 4'-acetyl- (MeTTP) and 4'-propanoylthymidine 5'-triphosph...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Marx, A, Amacker, M, Stucki, M, Hübscher, U, Bickle, T A, Giese, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147810/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9705520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.17.4063
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