4'-Acylated thymidine 5'-triphosphates: a tool to increase selectivity towards HIV-1 reverse transcriptase.

4'-Acylated thymidines represent a new class of DNA chain terminators, since they have been shown to act as post-incorporation chain-terminating nucleotides despite the presence of a free 3'-hydroxyl group. Here, we describe the action of the 4'-acetyl- (MeTTP) and 4'-propanoylthymidine 5'-triphosph...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

I whakaputaina i:	Nucleic Acids Res
Ngā kaituhi matua:	Marx, A, Amacker, M, Stucki, M, Hübscher, U, Bickle, T A, Giese, B
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Oxford University Press 1998
Ngā marau:	Research Article
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147810/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9705520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.17.4063
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!