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Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue

Patterning of the embryonic endoderm into distinct sets of precursor cells involves the precisely regulated activities of key transcription regulators. Ectopic, pan-endodermal activation of XPtf1a/p48 during pancreas precursor cell stages of Xenopus embryogenesis results in an expansion of the pancr...

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Autores principales: Afelik, Solomon, Chen, Yonglong, Pieler, Tomas
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1475757/
https://ncbi.nlm.nih.gov/pubmed/16751182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.378706
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