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The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

We have generated a mouse bearing a null allele of the gene encoding basic helix–loop–helix (bHLH) protein p48, the cell-specific DNA-binding subunit of hetero-oligomeric transcription factor PTF1 that directs the expression of genes in the exocrine pancreas. The null mutation, which establishes a l...

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Hlavní autoři: Krapp, Andrea, Knöfler, Martin, Ledermann, Birgit, Bürki, Kurt, Berney, Catherine, Zoerkler, Nicole, Hagenbüchle, Otto, Wellauer, Peter K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1998
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC317250/
https://ncbi.nlm.nih.gov/pubmed/9851981
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