The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

We have generated a mouse bearing a null allele of the gene encoding basic helix–loop–helix (bHLH) protein p48, the cell-specific DNA-binding subunit of hetero-oligomeric transcription factor PTF1 that directs the expression of genes in the exocrine pancreas. The null mutation, which establishes a l...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Krapp, Andrea, Knöfler, Martin, Ledermann, Birgit, Bürki, Kurt, Berney, Catherine, Zoerkler, Nicole, Hagenbüchle, Otto, Wellauer, Peter K.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 1998
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317250/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9851981/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.23.3752
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