Mismatched nucleotides may facilitate expansion of trinucleotide repeats in genetic diseases.

We have studied the contribution of mismatch sequences to the trinucleotide repeat expansion that causes hereditary diseases. Using an oligonucleotide duplex, (CAG)5/(CTG)5, as a template-primer, DNA synthesis was carried out using either Escherichia coli DNA polymerase I (Klenow fragment) or human...

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Номзүйн дэлгэрэнгүй

-д хэвлэсэн:	Nucleic Acids Res
Үндсэн зохиолчид:	Nakayabu, M, Miwa, S, Suzuki, M, Izuta, S, Sobue, G, Yoshida, S
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Oxford University Press 1998
Нөхцлүүд:	Research Article
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9518492/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.8.1980
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