G-Quadruplex Formed by the Promoter Region of the <i>hTERT</i> Gene: Structure-Driven Effects on DNA Mismatch Repair Functions

G-quadruplexes (G4s) are a unique class of noncanonical DNAs that play a key role in cellular processes and neoplastic transformation. Herein, we focused on the promoter region of human <i>TERT</i> oncogene, whose product is responsible for the immortality of cancer cells. It has been shown by chemi...

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Principais autores:	Anzhela V. Pavlova, Victoria Yu. Savitskaya, Nina G. Dolinnaya, Mayya V. Monakhova, Anastasia V. Litvinova, Elena A. Kubareva, Maria I. Zvereva
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-08-01
coleção:	Biomedicines
Assuntos:	<i>hTERT</i> promoter G-quadruplex DNA mismatch repair MutS MutL
Acesso em linha:	https://www.mdpi.com/2227-9059/10/8/1871
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